Endocrine Abstracts

Pseudoacromegaly is associated with acromegalic phenotype but normal insulin like growth factor-1 (IGF-1) levels and suppressed growth hormone levels. The reasons of this condition may be pachydermoperiostitis insulin resistance, drug intake such as minoxidil and hypothyroidism (4). We describe pachydermoperiostitis in a patient with hyperthyroidism and non-secretory pituitary macroadenomas.Clinical case: A 62 year old man presented with palpitation, swe...

Prolactinoma is the most common cause of chronic hyperprolactinemi and drugs that rise serum prolactin levels have been ruled out. Altough almost all of them arise within the sella turcica, there are some rare cases in which prolactinoma is located outside the intrasellar region, so it is defined as ectopic prolactinoma. Neuroleptics (e.g., haloperidol, chlorpromazine, risperidone.) can elevate serum PRL to levels that usually are detected with prolactinomas. We report a case ...

Background-aim: Tendency to autoimmune diseases has been reported to be increased in beta thalassemia minor (BTM). Our aim was to examine the prevalence of thyroid autoimmunity in BTM.Method: Eighty six adults with BTM and 93 age and gender matched controls were included in the study. The two groups were compared cross-sectionally in terms of anti-thyroid antibodies (anti-TG and anti-TPO) and thyroid hormones. Patients with known autoimmune disorders oth...

The main hormones responsible for the incretin effect are GIP and GLP-1. Thyroid hormones accelerate the absorption of glucose from the intestine, increase the release of glucose from glycogen stores and affect the hepatic demolition of insulin. We aimed to assess incretin levels in patients with hyperthyroidism before and after thyroxine therapy. Total 24 subjects (12 hyperthyroid and 12 controls) were enrolled in the study. Oral glucose tolerance test was performed in patien...

Introduction: Parathormone (PTH) is one of the major regulator of the bone and mineral metabolism. Elevated PTH levels in patients with primary and secondary hyperparathyroidism is thought to have negative effects on the cardiovascular system. In our study, we aimed to investigate a possible relationship between plasma PTH levels and coronary atherosclerosis.Methods: Fourty-two men and 35 women, a total of 77 patients were included the study who admitted...

Introduction: Hyperthyroidism is associated with asymptomatic hypercalcaemia due to increased calcium mobilization from bone and catecholamine metabolism. Hypercalcaemia secondary to hyperthyroidism coexist with decreased or normal parathyroid hormone level. We reported case of 30-year-old man who suffered from Graves’ disease and primary hyperparathyroidism.Case report: A 30-year-old male patient was admitted to our hospital suffered from palpitati...

Introduction: Klinefelter syndrome (KS) is the most common chromosomal disorder characterized by clinical features of hypogonadism and infertility. Portal vein aneurysms are very rare clinic findings. Reported cases are increasing due to use of modern imaging techniques in clinic practise.Case report: 19-year-old man was admitted to our hospital with complaints of abdominal pain, nausea, and vomiting associated with eating. He was recently diagnosed with...

A 21-year-old female (height: 148 cm, weight: 38 kg, and BMI: 17) was referred to our endocrinology outpatient polyclinic with the complaints of severe abdominal pain and severe hypertriglyceridemia. The patient’s medical history revealed diabetes and FMF. Physical examination revealed a marked loss of subcutaneous fat from the extremities leading to prominence of muscular contours and veins, with excess fat around the face, submental and dorsocervical region. Despite the...

Background and aim: It was known that NT-proBNP levels increased in cardiac failure. But, NT-proBNP levels in different thyroid status still unclear. We aimed to evaluate serum NT-proBNP levels in both of hyperthyroid and hypothyroid patients without cardiac insufficiency.Subjects and methods: Thirty nine patients with hyperthyroidism (43.0±16.5 yr), 25 patients with hypothyroidism (35.4±13.9 yr) and 34 ages matched euthyroid subjects (41.4&#17...

Pituitary apoplexy (PA) is an endocrine emergency characterized by acute, severe headache, visual disturbances, ophthalmoplegia, hypopituitarism and altered consciousness. This condition usually arises in an underlying pituitary adenoma. 27-year-old female without a known pitutary lesion presented to the emergency department in December 2015 with a 8-hour history of with sudden and severe frontal headache, fever, blurred vision, nausea, confusion at 36 weeks of gestation. The ...